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WPRE element

Woodchuck Hepatitis Virus (WHP) Posttranscriptional Regulatory Element (WPRE) is a DNA sequence that, when transcribed creates a tertiary structure enhancing expression. Commonly used in molecular biology to increase expression of genes delivered by viral vectors. Insertion of the WPRE in the 3' untranslated region of coding sequences carried by either oncoretroviral or lentiviral vectors substantially increased their levels of expression in a transgene-, promoter- and vector-independent manner.

  • Part ID EV8DLV
  • Name WPRE element
  • Alternative Name -
  • Version -
  • Division -
  • Parent Sequence -
  • Collection -
  • Part Status Valid
  • Public check_circle
  • Certified highlight_off
  • Length 598
  • Source Strain Other/Unknown/Synthetic
  • Suitable for
    M
  • Registry Code -
  • Contains
  • Created by OfficinaeBio
  • Created at Jan. 5, 2017, 4:42 p.m.
  • Last Edit Jan. 5, 2017, 4:42 p.m.
Biomodule Seq
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